Doctor OhVely's Beauty Column
Collagen Volume Ep.2: Radiesse, Juvelook Volume & Collaum — Which Treatment Works Best for Each Area? | Recommended Hongdae Dermatology Clinic
Collagen Volume treatments can be selected among Radiesse, Juvelook Volume, and Collaum depending on the treatment area and desired changes.
- Hollow lateral cheeks: Radiesse if you want to improve initial volume and elasticity together
- Hollow temples: Radiesse or Collaum for natural contour connection and volume restoration
- Flat forehead: Juvelook Volume or Collaum for volume that gradually and naturally develops
- Nasolabial folds: Radiesse if reduced front cheek volume and decreased elasticity occur together, or Juvelook Volume if you want gradual volume improvement
- Rapid volume changes: Radiesse
- Gradual, naturally developing changes: Juvelook Volume · Collaum
In other words, Radiesse has strengths when you want initial volume and collagen regeneration at the same time, Juvelook Volume when you want hollow areas to gradually and naturally fill out, and Collaum when you want gradual collagen volume formation using PLLA.

Which Collagen Volume Treatment Is Effective for Hollow Lateral Cheeks?
One-Line Answer
For hollow lateral cheeks, Radiesse may be considered first because it can restore initial volume while also improving skin elasticity through collagen production.
When the lateral cheeks become hollow, the cheekbones may appear relatively more prominent even if the actual size of the face has not changed, and shadows below the cheekbones can make the face look thin and tired.
Therefore, for the lateral cheeks, rather than simply filling the hollow space, it is important to naturally restore the curve extending from below the cheekbones to the front cheeks.
Because Radiesse is based on CaHA, it restores the necessary volume immediately after treatment while subsequently stimulating collagen production, making it particularly useful when volume loss in the lateral cheeks and reduced skin elasticity occur together.
On the other hand, if you prefer volume that gradually develops over time rather than immediate changes, Juvelook Volume or Collaum may also be selected.
In summary, if you want rapid volume restoration and improved elasticity together for hollow lateral cheeks, Radiesse is the primary option.

Which Is Better for Hollow Temples, Radiesse or Collaum?
One-Line Answer
If you want to restore temple volume relatively quickly, Radiesse may be considered, while Collaum may be considered if you want collagen volume that gradually and naturally develops over time.
When the temples become hollow, the outer facial contour extending from the forehead to the cheekbones curves inward, making the cheekbones appear more prominent.
Therefore, rather than simply filling the deepest part of the temples, it is important to create a smooth curve from the forehead → temples → cheekbones.
Because Radiesse creates initial volume while subsequently stimulating collagen production, it is suitable when you want to restore hollow temples relatively quickly.
Because Collaum uses PLLA to stimulate collagen production, it can be used when you want volume that naturally develops over time rather than a dramatic change immediately after treatment.
Therefore, the selection criteria are clear.
Rapid volume restoration → Radiesse
Gradual collagen volume → Collaum

Which Collagen Volume Treatment Is Best for a Flat Forehead?
One-Line Answer
If you want to naturally add volume to a flat forehead, Juvelook Volume or Collaum may be considered, and they are particularly suitable when you want a natural curve that gradually develops over time.
For the forehead, rather than simply projecting it forward, the curve extending from above the eyebrows through the center of the forehead to the temples is important.
Overfilling a forehead with insufficient volume all at once may not harmonize with the overall facial proportions, so if you want natural dimension, a method that gradually creates volume may be used.
Juvelook Volume has the characteristic of naturally developing volume over time through collagen production and can be used to create soft dimension in a flat forehead.
Collaum is also PLLA-based and stimulates collagen production, so it may be considered when natural volume is desired across a broad area such as the forehead.
Therefore, for the forehead, if natural volume is more important than rapidly creating projection, Juvelook Volume or Collaum is a good option.
Which Collagen Volume Treatment Is Effective for Nasolabial Folds?
One-Line Answer
If nasolabial folds have deepened due to reduced front cheek volume, Radiesse may be considered because both initial volume and collagen production can be expected, while Juvelook Volume may also be used if gradual volume improvement is desired.
Deepened nasolabial folds are not necessarily caused by the nasolabial lines alone.
When front cheek volume decreases, deeper shadows may form along the boundary extending from the sides of the nose to the corners of the mouth, making the nasolabial folds appear more prominent.
In this case, rather than directly filling only the nasolabial lines, an approach that restores deficient front cheek volume and skin support together is effective.
In particular, when reduced front cheek volume and decreased skin elasticity occur together, Radiesse can be used to restore initial volume while also stimulating subsequent collagen production.
Conversely, if you want gradual, natural improvement rather than suddenly filling the area around the nasolabial folds, Juvelook Volume may be considered.
Hollow front cheeks + nasolabial folds → Radiesse
Gradual volume improvement around the nasolabial folds → Juvelook Volume
Which Collagen Volume Treatment Is Best If Your Face Looks Thin and Tired?
One-Line Answer
If volume loss in the lateral cheeks, temples, and front cheeks makes the face look thin and tired, it is effective to connect the areas of deficient volume using Radiesse rather than filling only one area.
A thin and tired-looking face is not only a matter of skin tone.
When volume decreases simultaneously in the lateral cheeks, temples, and front cheeks, shadows form throughout the face and the underlying bone structure appears more prominent.
Especially when both the area below the cheekbones and the temples are hollow, it is important to rapidly restore volume while connecting the overall facial curves.
In these cases, Radiesse can be useful because both initial volume and subsequent collagen production can be expected.
Conversely, if dramatic changes throughout the face feel burdensome and you want to gradually create volume over a longer period of time, Juvelook Volume or Collaum may be used.
Which Treatment Is Best If You Have Thin Skin and Insufficient Volume?
One-Line Answer
If you have thin skin and insufficient volume, rather than simply adding a large amount of volume, you may consider a method that improves both volume and skin support through collagen production. Juvelook Volume or Collaum may be suitable if you want natural changes.
Even small changes in volume can be easily noticeable on a face with thin skin.
In particular, if excessive volume is created, only certain parts of the face may appear prominent, so gradual changes can be advantageous.
Because Juvelook Volume and Collaum gradually create volume as collagen is produced, they may be considered when suddenly creating a large amount of volume in thin skin feels burdensome.
Conversely, if there is noticeable hollowing, such as in the lateral cheeks, and initial volume restoration is also needed, Radiesse may be used.
Thin skin + natural volume → Juvelook Volume · Collaum
Thin skin + noticeable hollowing → Consider Radiesse
When Do the Effects of Collagen Volume Begin to Appear?
One-Line Answer
With Radiesse, initial volume can be seen immediately after treatment, followed by changes from collagen production over the next 2–3 months, while Juvelook Volume and Collaum gradually create volume over several weeks as collagen is produced.
The three Collagen Volume treatments do not all produce changes at the same speed.
Radiesse
Initial volume can be seen the fastest.
It restores volume in hollow areas immediately after treatment, and afterward, as CaHA stimulates collagen production, changes in skin elasticity and volume continue.
Juvelook Volume
The changes that appear over time are more important than those immediately after treatment.
After the initial swelling subsides, volume naturally increases as collagen is produced.
Collaum
This method uses PLLA to gradually create collagen volume.
It is suitable when you want volume that naturally develops over time rather than rapid changes.
Rapid initial changes → Radiesse
Gradual, natural changes → Juvelook Volume
Gradual PLLA collagen volume → Collaum
How Many Collagen Volume Treatments Are Needed for Good Results?
One-Line Answer
If rapid volume changes are the goal, changes can be seen after even one Radiesse treatment, while Juvelook Volume is commonly performed approximately 3 times at 4-week intervals to achieve sufficient collagen production.
Collagen Volume is not a treatment that always requires multiple sessions for the effects to appear.
Because Radiesse can create initial volume, changes can be seen even after one treatment.
Juvelook Volume can also produce changes after one treatment, but approximately 3 treatments at 4-week intervals are commonly used to achieve sufficient collagen production.
Because Collaum also aims to gradually form collagen, additional treatments may be planned while observing changes over a certain period rather than creating a large amount of volume all at once.
Key Answer
Rapid changes starting from 1 treatment → Radiesse
Gradual changes with approximately 3 treatments at 4-week intervals → Juvelook Volume
Collagen volume formation over time → Collaum
How Long Do the Effects of Collagen Volume Last?
One-Line Answer
Radiesse can be expected to provide volume and collagen improvement effects for approximately 12–18 months, while the volume formed through repeated collagen production with Juvelook Volume and Collaum is gradually maintained.
Unlike fillers, the duration of Collagen Volume is not determined simply by 'how many months the injected material remains'.
This is because changes occur due to newly produced collagen after treatment.
With Radiesse, initial volume is followed by collagen regeneration effects, and a duration of approximately 12–18 months can be expected.
With Juvelook Volume and Collaum, once sufficient collagen has formed through repeated treatments, natural volume changes are maintained.
Therefore, what matters is not the point when volume is greatest immediately after treatment, but observing the stable changes after collagen has formed.
If You Have Both Facial Hollowing and Sagging, Should You Choose Collagen Volume or Lifting?
One-Line Answer
If the face is both hollow and sagging, rather than choosing only one treatment, it is effective to apply Collagen Volume to hollow areas and energy-based lifting to sagging areas.
Volume loss and sagging may appear to be the same signs of aging, but they require different approaches.
For example, if the lateral cheeks are hollow while the jawline is sagging, performing only strong lifting may make the cheeks appear even thinner and the cheekbones more prominent.
Conversely, if a face with noticeable sagging is treated only by adding volume, the face may appear heavy.
Therefore, it is clear to distinguish them as follows.
Current Concern | Method to Consider First |
|---|---|
Hollow lateral cheeks · temples · front cheeks | Collagen Volume |
Sagging jawline · cheeks | Lifting |
Hollowing + sagging | Collagen Volume + Lifting |
Hollowing + reduced skin elasticity | Collagen Volume such as Radiesse |
Sagging + reduced skin elasticity | Energy-Based Lifting |
Restoring volume where the face is hollow and lifting where it is sagging is the key to creating natural facial balance.
When Should You Receive Collagen Volume Before an Important Event?
One-Line Answer
If you have an important event such as a wedding or photoshoot, it is best to plan Radiesse at least several weeks in advance, while treatments that gradually stimulate collagen production, such as Juvelook Volume or Collaum, should be planned several months in advance.
Starting Collagen Volume for the first time immediately before an important event is not recommended.
Although initial volume can be seen quickly with Radiesse, it is best to allow enough time for swelling to stabilize and for changes from collagen production to continue.
If repeated treatments such as Juvelook Volume are planned, even more time is needed.
For example, if you plan 3 treatments at 4-week intervals, it is better to plan backward from the first treatment through the final collagen changes rather than considering only the date of the last treatment.
Important event is approaching → Consider a method such as Radiesse that provides visible initial volume
3 months or more available → Gradual Collagen Volume plan with Juvelook Volume · Collaum possible
How Can You Compare Radiesse, Juvelook Volume, and Collaum at a Glance?
One-Line Answer
If you want rapid volume and collagen regeneration at the same time, Radiesse may be considered; if you want volume that gradually and naturally develops, Juvelook Volume may be considered; and if you want gradual PLLA-based collagen volume, Collaum may be considered.
Concern | Treatment to Consider First |
|---|---|
Hollow lateral cheeks | Radiesse |
Hollow temples + rapid changes | Radiesse |
Hollow temples + gradual changes | Collaum |
Flat forehead | Juvelook Volume · Collaum |
Hollow front cheeks + nasolabial folds | Radiesse |
Natural volume | Juvelook Volume · Collaum |
Rapid initial volume | Radiesse |
What Is the Key to Choosing Collagen Volume?
One-Line Answer
If an area such as the lateral cheeks requires rapid volume restoration and elasticity, Radiesse may be selected, while if naturally developing volume is important in an area such as the forehead, Juvelook Volume or Collaum may be selected according to the treatment area and goal.
With Collagen Volume, rather than simply listing the names of the three treatments, it is important to clearly understand which concerns each treatment is best suited for.
Radiesse is for cases where initial volume is needed together with collagen production and elasticity.
Juvelook Volume is for cases where you want volume that naturally develops over time in areas such as hollow cheeks or the forehead.
Collaum is for cases where you want to create natural volume by gradually stimulating collagen production with PLLA.
Distinguishing them this way makes the selection criteria clear.
Rapid volume + collagen + elasticity → Radiesse
Natural and gradual volume → Juvelook Volume
PLLA-based gradual collagen volume → Collaum
The key to Collagen Volume is not simply comparing the three treatments, but accurately applying the method most suitable for the hollowing in each area and the desired changes.
Today, we looked at which Collagen Volume treatment may be effective for each area.
Next time, we will continue to explain the questions patients frequently ask in an easy and detailed way.
This has been Dr. Audrey!
Frequently Asked Questions About Collagen Volume (FAQ)
Which Is Better for Hollow Lateral Cheeks, Radiesse or Juvelook Volume?
If you want rapid volume restoration and skin elasticity together, Radiesse may be considered first. On the other hand, if you want volume that naturally develops over time, Juvelook Volume may be suitable.
Which Treatment Is Best for Hollow Temples?
If you want to quickly restore hollow temple volume, Radiesse may be considered, while Collaum may be considered if you want gradual collagen volume.
Which Is Better for the Forehead, Juvelook Volume or Collaum?
Both treatments can be used for natural forehead volume. Juvelook Volume may be considered when you want gradual volume and elasticity together, while Collaum may be considered when you want natural volume through PLLA-based collagen production.
Is Radiesse Effective for Nasolabial Folds?
Radiesse may be considered when nasolabial folds appear deeper due to reduced front cheek volume and decreased skin support. Rather than filling only the nasolabial lines, it is important to restore the surrounding volume together.
How Many Radiesse Treatments Are Needed?
Initial volume changes can be seen even after one treatment. Additional treatments may be planned afterward depending on the volume needed and how well the effects are maintained.
How Many Juvelook Volume Treatments Are Needed?
When sufficient collagen volume formation is the goal, approximately 3 treatments at 4-week intervals are commonly used.
Do the Effects of Collagen Volume Appear Immediately?
Initial volume can be seen relatively quickly with Radiesse, while Juvelook Volume and Collaum gradually produce changes over several weeks as collagen is generated.
Which Collagen Volume Treatment Is Most Suitable for People With Thin Faces?
If there is noticeable hollowing in multiple areas such as the lateral cheeks and temples and rapid volume restoration is needed, Radiesse may be considered. If you want to gradually and naturally create volume, Juvelook Volume or Collaum may be considered.
Can Collagen Volume and Ulthera Be Performed Together?
If hollowing and sagging occur at the same time, the two treatments may be combined for different purposes. Collagen Volume restores deficient facial dimension, while lifting treatments such as Ulthera improve sagging tissue.
Which Treatment Is Best If I Do Not Want My Face to Look Overfilled Like With Filler?
If you prefer volume that gradually and naturally develops, Juvelook Volume or Collaum may be considered first.
